Introduction: It has been established that 30% to 50% of children with autism suffer from epilepsy. Its proper management and efficient control requires the application of anti-epileptic drugs.
Aim: The aim of this study is to assess the effects of some anti-epileptic drugs on oral health in childhood age.
Material and Methods: A male child at the age of 8 years with a mixed dentition, with diagnosed autism and epilepsy was examined. The following diagnostic indicators were used: dft/DMFT, PLI, GI, PBI, as well as an enquiry.
Conclusion: The obtained results confirm the role of the individual general health and the influence of anti-convulsant therapy on the oral-dental state under conditions of autism and diagnosed epilepsy.
Пенева М. Зъбният кариес през 21 век. Второ издание; 2012.
Dongari-Bagtzoglou A. Research, Science and Therapy Committee, American Academy of Periodontology. Drug-associated gingival enlargement. J Periodontol. 2004; 75:1424–31. [PubMed] [Google Scholar]
Ghafoor PA, Rafeeq M, Dubey A. Assessment of oral side effects of Antiepileptic drugs and traumatic oro-facial injuries encountered in Epileptic children. J Int Oral Health. 2014 Apr;6(2):126-8. Epub 2014 Apr 26. PMID: 24876713; PMCID: PMC4037794.
Gurbuz T, Tan H. Oral health status in epileptic children. Pediatr Int. 2010; 52:279-83. Epub 2009 Sept 15.
https://adapt.bg/
https://www.autismawareness.com.au/aupdate/epilepsy-and-autism
https://www.nhs.uk/conditions/autism/signs/children/
https://thefuturedentistry.com/indices/
Jacobsen PL., Eden O. Epilepsy and the dental management of the epileptic patient. J Contemp Dent Pract2008; 9(1):54-62.
Johnston MV, Seizures in childhood; Nelsons textbook of Pediatrics 2004 17th edPennsylvania Saunders:1993-2008. [Google Scholar]
Joshi SR, Pendyala GS, Saraf V, Choudhari S, Mopagar V. A comprehensive oral and dental management of an epileptic and intellectually deteriorated adolescent. Dent Res J (Isfahan). 2013 Jul;10(4):562-7. PMID: 24130597; PMCID: PMC3793425.
Joshi NH, Deshpande AN, Deshpande NC, Rathore AS. Comparative evaluation of oral hygiene status and gingival enlargement among epileptic and healthy children as related to various antiepileptic drugs. J Indian Soc Periodontol. 2017 Mar-Apr;21(2):125-129. doi: 10.4103/jisp.jisp_48_17. PMID: 29398857; PMCID: PMC5771109.
Károlyházy K, Kovács E, Kivovics P, Fejérdy P, Arányi Z. Dental status and oral health of patients with epilepsy: An epidemiologic study. Epilepsia 2003; 44:1103‑8.
Mehmet Y, Senem O, Sulun T, Humeyra K. Management of epileptic patients in dentistry. Surg Sci. 2012; 3:47–52.
Peter S. Essentials of Preventive and Community Dentistry. 4th ed. New Delhi: Arya Publishing House; 2009. p. 420.p. 422. J Can Dent Assoc 2011; 71: b140.
Suneja B, Chopra S, Thomas AM, Pandian J. A Clinical Evaluation of Gingival Overgrowth in Children on Antiepileptic Drug Therapy. J Clin Diagn Res. 2016 Jan;10(1): ZC32-6. doi: 10.7860/JCDR/2016/16443.7069. Epub 2016 Jan 1. PMID: 26894172; PMCID: PMC4740700.
Tan H, Gurbuz T, Dagsuyu IM, Gingival enlargement in children treated with antiepileptics J Child Neurol 2004 19(12):958-63. [Google Scholar]
Vacharotayangul P, Lozadanur F. Drug induced gingival hyperplasia. http://www.emedicine.com/derm/topic645.htm [Google Scholar]