Ювенилният назофарингеален ангиофибром е рядък съдов тумор, срещащ се с честота под 0,5% от всички тумори на главата и шията. Въпреки че е хистологично бенигнен, той притежава локална инвазивност, подобно на злокачествените неоплазми. Лечението до ден-днешен е сериозно предизвикателство, криещо множество рискове от тежки, понякога животозастрашаващи усложнения.
Juvenile nasopharyngeal angiofibroma is a rare high vascular tumor with a frequency of less than 0,5% of all head and neck tumors. Although histologicaly benign, it possess invasiveness similar to malignant neoplasms. The treatment is still a challenge with risk of sometimes lifethreatening complications.
Wu AW, Mowry SE, Vinuela F, Abemayor E, Wang MB. Bilateral vascular supply in juvenile nasopharyngeal angiofibromas. Laryngoscope. Mar 2011;121(3):639-43
Yi Z, Fang Z, Lin G, Lin C, Xiao W, Li Z, et al. Nasopharyngeal angiofibroma: A concise classification system and appropriate treatment options. Am J Otolaryngol. Jan 15 2013
Mattei TA, Nogueira GF, Ramina R. Juvenile Nasopharyngeal Angiofibroma with Intracranial Extension. Otolaryngol Head Neck Surg. May 13 2011
Chakraborty S, Ghoshal S, Patil VM, Oinam AS, Sharma SC. Conformal radiotherapy in the treatment of advanced juvenile nasopharyngeal angiofibroma with intracranial extension: an institutional experience. Int J Radiat Oncol Biol Phys. Aug 1 2011;80(5):1398-404.
Cloutier T, Pons Y, Blancal JP, Sauvaget E, Kania R, Bresson D, et al. Juvenile nasopharyngeal angiofibroma: does the external approach still make sense?. Otolaryngol Head Neck Surg. Nov 2012;147(5):958-63.
Tang IP, Shashinder S, Gopala Krishnan G, Narayanan P. Juvenile nasopharyngeal angiofibroma in a tertiary centre: ten-year experience. Singapore Med J. Mar 2009;50(3):261-4.
Succo G, Gisolo M, Crosetti E, Bergui M, Danesi G. Spontaneous ICA rupture: A severe late complication after giant nasopharyngeal angiofibroma resection. Int J Pediatr Otorhinolaryngol. Jan 8 2013
De Vincentiis M, Gallo A, Minni A, Torri E, Tomassi R, Della Rocca C. [Preoperative embolization in the treatment protocol for rhinopharyngeal angiofibroma: comparison of the effectiveness of various materials]. Acta Otorhinolaryngol Ital. Jun 1997;17(3):225-32
