РРП е заболяване, причинено от HPV. Патохистологично се различават два вида папиломи – меки и твърди, което е от значение както за начина на предаване на инфекцията, така и за прогнозата на заболяването. Характерни за ювенилната форма на РРП са меките папиломи, където преобладава рехавата и богато кръвоснабдена строма. Основният начин за заразяване на детето при тази форма е предаването на инфекцията от инфектирания родов канал на майката по време на раждането. Съществуват и други фактори като имунен статус, продължителност и сила на действие на вируса, травма и др, които са съществени за появата и развитието на РРП.
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RRP is a disease caused by HPV. Pathohystologically there are two types of papillomas – hard and soft, which is significant both for the spreading of the infection and the end of the disease. The soft papillomas are typical for the juvenile form of RRP, where the richly blood supplied and loose stromas are predominating. The main way for spreading the disease to the child in this form is by the infected birth channel of the mother during the childbirth. Other factors exist like immune status, continuality and intensity of the action of the virus, trauma and others which are essential for the appearance and development of the RRP.
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