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Serum lipid anomalies in adult patients with acute ischemic stroke

Daniela Yordanova Arabadzhieva, Zdravko Slavov, Ara Kaprelyan

Abstract

Introduction: There is rising evidence of the role of hyperlipidemia and dyslipidemia in the development of acute ischemic stroke (AIS). There is a considerable risk for AIS in adult individuals with these abnormalities. Our purpose was to reveal the incidence rate of the disorders of lipid metabolism in adult AIS patients.

Material and methods: We examined 129 male and 129 female patients with AIS at a mean age of 70.59±7.22 years hospitalized in the First Clinic of Neurology, St. Marina University Hospital of Varna in 2007-2013. The serum levels of total cholesterol, triglycerides, HDL- and LDL-cholesterol at admission were examined. Statistical data processing was performed by ANOVA as t-criterion was considered significant if p<0.05.

Results: The mean values of total cholesterol and LDL-cholesterol were slightly elevated while those of triglycerides were slightly reduced. The mean values of total cholesterol and triglycerides were higher in males than in females. Total cholesterol values were considerably more commonly higher in females than in males as the mean total cholesterol concentrations were higher in the female patients with normal, decreased and increased levels of this parameter. LDL-cholesterol was more commonly elevated as its mean values were higher in the female patients with its normal, decreased and increased levels.

Conclusion: A regular control of the parameters of lipid metabolism and keeping-up the healthy life-style in adult individuals and in patients with cardiovascular diseases could ensure a successful prevention of ischemic stroke.


Keywords

acute ischemic stroke; total cholesterol; triglycerides; HDL-Cholesterol, LDL-Cholesterol

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DOI: http://dx.doi.org/10.14748/ssm.v47i2.1056
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About The Authors

Daniela Yordanova Arabadzhieva
Department of neurology and neurosciences
Bulgaria

Medical university of Varna

Zdravko Slavov
Varna free university
Bulgaria

Department of informatics

Ara Kaprelyan
Department of neurology and neurosciences
Bulgaria

Medical university of Varna

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