Stroke is without any doubt among the top reasons for disability and mortality in neurology. This is especially true in Bulgaria, where vascular diseases in general, and cerebrovascular disease (CVD) in particular, are significantly more prevalent than in other European countries. More than 80`000 cases of CVD are registered yearly in Bulgaria, over 35`000 having stroke (1). Speaking of stroke, we should not underestimate the other manifestations of CVD, such as transient ischemic attacks and vascular cognitive impairment. The disease may develop silently or cause non-specific complaints for years, and only then become clearly symptomatic. For this reason the diagnosis of CVD can be delayed, which usually leads to less successful prophylaxis and treatment.
Milanov I, Stamenova P.(Eds.) National consensus statement for prophylaxis, diagnosis and treatment of cerebrovascular disease. Balgarska nevrologiya. 2013;14(3 Suppl.1):170-178.
Miglani N, Bains K. Interplay between Proteins and Metabolic Syndrome- A Review. Crit Rev Food Sci Nutr. 2015 Jun 5:0. [Epub ahead of print]
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009 Oct 20;120(16):1640-1645.
Aloe L, Tonchev A, Fiore M, Chaldakov G. Homo Diabesus: Involvement Of Metabotrophic Fact. Adipobiology. 2013;5:45-49.
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002 Dec 17;106(25):3143-3421.
van Rooy MJ, Pretorius E. Metabolic syndrome, platelet activation and the development of transient ischemic attack or thromboembolic stroke. Thromb Res. 2015 Mar;135(3):434-442.
Rodriguez-Colon SM, Mo J, Duan Y, Liu J, Caulfield JE, Jin X, et al. Metabolic syndrome clusters and the risk of incident stroke: the atherosclerosis risk in communities (ARIC) study. Stroke. 2009 Jan;40(1):200-205.
Email this article (Login required) 
