Development of new polymer systems (PS) based on thermo-active resins is important not only from a chemical viewpoint but also because of the opportunity for programmable changing their properties and subsequent application in clinical practice. Some chemical features of a new composition for a multicomponent polymer system (MPS) based on hydrophilized unsaturated polyester resin (HUPR) are presented. Strength parameters of several resins of different compositions are examined. The analysis of the acute oral toxicity of these resins in white Wistar rats proves that they are low toxic. These PS do not demonstrate any harmful effects on human skin after the predicting irritation and sensitization tests using epicutaneous samples. Their main advantages include preliminary water-solubility and capacity to incorporate water, good dilution into water and resin water dispersions, porosity, low relative mass, high strength indices, improved ecological features, thin-founding capacity, good relief impressions in combination with high adhesion ability towards wet surfaces. A wide MPS usage in the manufacture of orthopedic plaster dressings, prostheses, splints, insoles, positive-sample dental imprints, and casts is recommended.
Байнова, A. Методи за определяне на кожната токсичност за хигиенни образования.- В: V. Конференция на експертите по профилактична токсикология. София, 1973.
Байнова, А. Експериментално проучване на ефекта на цетафарм върху кожата,- Хиг. и здравеоп., 22, 1979, № 2, 143-153.
Черкезова, Р. Ц. Многокомпонентна полимерна система на основата на хидрофилизирана ненаситена полиестерна смола и метод за получаването й. Патент на България, per. № 63158. Заявен през 1997 г. и издаден през 2001 г.
Черкезова, Р. Ц. Получение и исследование супермолекулярной структуры гидрофилизированной полимерной смолы.- Высокомол. соедин. (Москва), сер. Б, 34, 1992, № 8, 45-47.
Ballantyne, B., D. E. Dodd, D. J. Nachreiner , R. C. Myers. The acute toxicity and primary irritancy of N-benzyl-N,N-dimethylamine.-DrugChem. Toxicol., 8, 1985, No 1-2,43-56.
Bjarnason, B., E. Flosadottir, T. Fischer. Assessment of budesonide patch tests.- Cont. Dermat, 41, 1999, No 4, 211-217.
Bjarnason, B., E. Flosadottir , T. Fischer. Reactivity at edges of corticosteroid patch tests may be an indicator of a strong positive test response.- Dermatology, 199, 1999, No 2, 130-134.
Cherkezova, R. Ts., D. S. Todorova. Researching the topology of a two-component polymer system based on HUPER and UFR by means of infrared spectroscopic analysis.- Annu Proc. IMAB, 8, 2002, No 1, 143-145.
Fischer , T., H. 1. Maibach. Easier patch testing with TRUE Test.- J. Am. Acad. Dermatol., 20, 1989, No 3, 447-453.
Fischer , T., B. Kreilgard, H. I. Maibach. The true value of the TRUE Test for allergic contact dermatitis.- Curr. Allergy Asthma Rep., 1, 2001, No 4, 316-322.
Hours, М., E. Cardis , A. Marciniak, P. Quelin, J. Fabry. Mortality of a cohort in a polyamide-polyester factory in Lyon: a further follow-up.- Br. J. Ind. Med., 46, 1989. No 9, 665-670.
Kanerva, L., T. Estlander, K. Alanko, P. Pfaffli, R. Jo1anki. Occupational allergic contact dermatitis from unsaturated polyester resin in a car repair putty.- Int. J. Dermatol., 38, 1999, No 6, 447-452.
MacFarlane, A. W., R. K. Curley , C. M. King. Contact sensitivity to unsaturated polyester resin in a limb prosthesis.- Cont. Dermat., 15, 1986, No 5, 301-303.
Minamoto, K., M. Nagano, K. Yonemitsu, M. Futatsuka. Allergic contact dermatitis from unsaturated
polyester resin consisting of maleic anhydride, phthalic anhydride, ethylene glycol and dicyclopentadiene.- Cont. Dermat., 46, 2002, No 1, 62-63.
Minamoto, K., M. Nagano, T. Inaoka, M. Futatsuka. Occupational dermatoses among fibreglass-reinforced plastics factory workers.- Cont. Dermat., 46, 2002, No 6, 339-347.
Minamoto, K., M. Nagano, T. Inaoka, T. Kitano, K. Ushijima, Y. Fukuda , M. Futatsuka. Skin problems among fiber-glass reinforced plastics factory workers in Japan.- Ind. Health, 40, 2002, No 1, 42-50.
Peschanskaya , N., P. Yakushev, Yu. Khristova, A. Topliyska. Small strain velocity spectra of polymers and compounds.- Polym. Sei., 35, 1993, 1243-1246.
Pfaffl i, P., R. Jolanki , T. Estlander, K. Tarvainen, L. Kanerva. Identification of sensitizing diethyleneglycol maleate in a two-component polyester cement.- Cont. Dermat., 46, 2002, No 3, 170-173.
Radenkov, P., A. Topliyska, Sh. Shelyaskov. Modifiziertes Redoxsystem fur die Aushartung von ungesattigten Polyesterharzen.- ln: Proc. XIX International Conference on Reinforced Plastics. Karlovy Vary, 1997, p. 228.
Robatto, G., G Malinverno, J. Bootman. Development and implementation of a safety evaluation program for chemical fibers.- Regul. Toxicol. Pharmacol., 17, 1993, No 2, Pt. 1, 193-208.
Tarvainen, K., R. Jolanki, T. Estlander. Occupational contact allergy to unsaturated polyester resin cements.- Cont. Dermat., 28, 1993, No 4, 220-224.
Tarvainen, K., R. Jolanki, T. Estlander, O. Tupasela, P. Pfaf fl i, L. Kanerva. Immunologic contact urticaria due to airborne methylhexahydrophthalic and methyltetrahydrophthalic anhydrides.- Cont. Dermat., 32, 1995, No 4, 204-209.
Zeiger, E. NTP technical report on the toxicity studies of methyl ethyl ketone peroxide in dimethyl phthalate administered topically in F344/N rats and B6C3F1 mice.- Toxic. Rep. Ser., 18, 1993, No 1, CIO.
Email this article (Login required) 
