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Clinical Characteristics of Patients with Hypertensive Encephalopathy

D. Minchev


Hypertensive encephalopathy (HE) presents with motor, cognitive, psychic and pelvic-reservoir syndromes as well as with dysarthric, extrapyramidal and gate disturbances. The author analyzed the clinical picture of HE and related clinico-diagnostic, pathogenetic, and therapeutic problems. Nine patients, 5 females and 4 males aged between 43 and 72 years (mean age of 52,5 years) with a cardio-cerebral form of hypertension were examined. The diagnosis of HE was proved clinically as well as by electrocardiography, Doppler sonography, x-ray, magnetic resonance tomography, polysomnography, angiography and neuropsychological tests. Symptoms of a coordination and pyramidal-extrapyramidal syndrome and only of a coordination syndrome were established in 3 patients each, while symptoms of pyramidal and frontal corneal syndrome and of pyramidal and coordination syndrome - in 2 patients each. All the patients presented with cognitive and memory disorders. The antiphospholipid antibodies were elevated in 6 patients. Treatment with vasodilatators, calcium antagonists, neuroprotective means, antioxidants, and Cholinesterase inhibitors did not cause any subjective and objective improvement of the neurological deficit The diagnostic criteria of HE clinical signs wee not well defined concerning the degree of their manifestation and specificity and they could indicate the onset of other nervous system diseases, too.


Hypertensive Encephalopathy; Pathophysiology; Clinical Syndromes

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About The Author

D. Minchev


D. Minchev, Dept. of. Neurology, Prof. Paraskev Stoyanov Medical University of Varna, BG-9002 Varna, 55 Marin Drinov St., Bulgaria

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