Aim: The aim of this paper was to analyze quantitatively the epithelium and lumen in all lobules of normal human prostates.
Materials and Methods: Samples of the prostate gland from all lobules were obtained during necropsy of prostates of 19 adult men aged 36-60 years without clinical symptoms of lesion of the urinary apparatus. The following variables were measured: number, length, width, area of acini, total gland area, area of the lumen and epithelial height using computerized morphometric techniques.
Results: The anteromedial lobule was characterized by the large size of the lumen of the alveoli: the length was 51.3±4.6 μm, the width was 102.2 ± 11 μm, the area was 3677±388 μm2 and the epithelial height was 16.9±1.1 μm (p<0.05). In the superomedial lobule respectively, the sizes of the alveoli were: length - 68.4±10.1 μm, width - 51.3±4.6 μm, area - 48372±4633388 μm2, and epithelial height - 16.9±1.1 μm.
The sizes of the inferolateral lobule and the posterolateral lobule did not differ significantly from each other (p>0.05): width - 28.4 and 36.9 μm, length - 60.9±8.7 and 60.4±12.1 mm, area of the alveoli - 1718±356 and 1650±08 μm2, epithelial height 15.8±1.4 and 17.0±0.6 μm.
Conclusion: There was a significant difference in the number, length, width of acini, total acinar area, area of the lumen, epithelial height of acini between different lobules of the prostate.
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