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Scripta Scientifica Medica

Estimation of the therapeutical value of dried polyphenolic extracts from two plants of dobrogea spontaneous flora

M. Bratu, F. Roncea, A. Popescu, Yoana Kiselova, Diana Ivanova

Abstract

Our study in volves Sophora japonica L. and Holoschoenus vulgaris L. both plants from Dobrogea` spontaneous flora. In order to establish the therapeutic value we measured the total polyphenol content (Folin - Ciocâlteu method) and the total antioxidant activity (by ABTS radical decolorization assay) of the dried extracts obtained under different working conditions. All the dried extracts` features presented are according to the general monograph Extracta quality conditions, <0,04% iron and heavy metals content, and dried substance <5%. The higher total antioxidant capacity and total polyphenol content were observed in Sophora extract no.1, correlated with a certain raw material/solvent ratio (1/5), time of extraction (8 hours). These preliminary data obtained for TEAC and TP content lead us to conclude that the extracts could have an important therapeutical value possibly confirmed by future studies involving animal testing.

Scripta Scientifica Medica 2007; 39(2):197-200


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DOI: http://dx.doi.org/10.14748/ssm.v39i2.499
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About The Authors

M. Bratu
Ovidius University of Constanta
Romania

Faculty of Dental Medicine and Pharmacy

F. Roncea
Ovidius University of Constanta
Romania

Faculty of Dental Medicine and Pharmacy

A. Popescu
Ovidius University of Constanta
Romania

Faculty of Dental Medicine and Pharmacy

Yoana Kiselova
Medical University of Varna
Bulgaria

Department of Preclinical, Clinical Pharmacology, Chemistry and Biochemistry

Diana Ivanova
Medical University of Varna
Bulgaria

Department of Preclinical, Clinical Pharmacology, Chemistry and Biochemistry

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