An 18-month-old female with granuloma annulare (GA), possibly related to morbilli-parotitis-rubella vaccination is reported. The first lesions started within ten days after injection and quickly disseminated over the distal aspects of the extremities. GA is relatively rare in this age group, and only anecdotal cases have been attributed to vaccination etiology. To the best of our knowledge, GA induced by morbilli-parotitis-rubella vaccination has not been described before. Speculations on the mechanical or immunological GA triggers related to the vaccinations, together with a comprehensive review of literature, are highlighted.
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