Objective: This retrospective study was conducted to follow out acute intoxications with neuroleptics in Varna region, to assess the frequency and proportion depending on other drug and non-pharmacological poisoning.
Methods: The objects of the study are 193 patients with acute neuroleptic intoxication treated in the Clinic of toxicology - VMA-MBAL-Varna. The study is retrospective and covers a period of 20 years (1991-2010).
Results: Incidence of acute poisoning with neuroleptics is 7.5% of all drug poisoning and 2.5% of general poisoning. Poisoning occurs commonly in women and the majority of poisonings are in people of working age.
Conclusion: In recent years, there is a trend for an increase in the absolute number and the proportion of poisonings with neuroleptics. Lethality in these poisonings is not high and is 0.4 percent.
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