Introduction: An odontogenic keratocyst (OKC) is a developmental cyst of the jaws characterized by aggressive growth and a high recurrence rate, leading to ongoing challenges in its classification and management.
Aim: This article aims to provide a comprehensive overview of the OKC, examining its etiology, clinical and radiographic features, histopathology, and current treatment strategies.
Materials and Methods: This review synthesizes information from relevant literature, including historical accounts of OKC classification, clinical case reports, and studies detailing its pathogenesis, histopathology, and treatment modalities.
Results: OKC presents with variable clinical features, often in the mandible, and radiographically appears as a well-defined radiolucent lesion. Histologically, it is characterized by a thin, parakeratinized epithelium. Treatment typically involves surgical removal, but recurrence is a concern.
Conclusion: An OKC remains a clinically significant lesion requiring careful diagnostic evaluation and tailored management to minimize recurrence and associated morbidity.
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