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Scripta Scientifica Medicinae Dentalis

Oral cavity changes in the course of infectious diseases, during childhood

Iliyan Todorov, Dimitrichka Bliznakova, Christiana Madjova, Tsvetan Tonchev, Margarita Gospodinova


Introduction: A number of infectious diseases, occurring in childhood take its clinical course with typical changes in the oral cavity. Those changes are pathognomonic sign of the disease or increase the clinical thinking about the concrete disease.

 Aim: In the present review we introduce the infectious diseases in childhood that cause different changes in the mouth. In accordance with it we set some tasks: to introduce pathophysiological mechanisms for mucosa damage and its role about diagnosis.

Materials and methods: We based on literature data about that problem. It is discussed in four aspects: diseases with enanthem, changes in the tongue, stomatitis and pharyngitis. Examples and pictures are given.

Conclusions: Our review presents that the throat inspection in the children with infectious diseases is important stage of clinical examination, should not be missed and the changes have to be recognized in details because of their great diagnostic and differential diagnostic significance.


rash; enanthema; infection; mouth; oral cavity; childhood

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Bliznakova B. Pediatrics for dentists. In: Diseases of the lips and oral mucosa. Varna; 2010. 395-412. Bulgarian.

D Genov, Lahtariev St, Stoicheva M, Komitova P, Geneva M. Changes in the mouth and throat. In: Symptoms and syndromes of infectious diseases. Sofia; 2007. 57-66. Bulgarian.

Dikov I, Zlatkov H, HIV-infection and AIDS in children. In: HIV-infection and AIDS. Plovdiv. 46-48. Bulgarian.

Taskov B. Diphtheria of the throat. Diphtheria. Plovdiv; 1960. 40-55.

Alcaide ML, Bison AL: Pharyngitis and epiglottitis. Infect Dis Clin North Am.2007;21:449-469.

Bisno AL. Acute pharyngitis. N Engl J Med. 2001 Jan;344(3):205-11.

Bisno AL, Gerber MA, Gwaltney JM Jr, et al: Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Clin Infect Dis. 2002;35:113-25.

Braunwald E, Fauci AS, Kasper DL, et al., eds. Harrison's Principles of Internal Medicine. 15th ed. New York, NY: McGraw-Hill; 2001.

Cunha BA. Group A streptococcal pharyngitis. Emerg Med. 1990;22:93-96.

Gerber MA. Diagnosis and treatment of pharyngitis in children. Pediatr Clin North Am. Jun 2005;52(3):729-47.

Gwaltney JM Jr, Bisno AL. Pharyngitis. In: Mandell GI, Bennett JE, Dolin R, eds. Mandell, Douglas & Bennett's Principles of Infectious Diseases. Vol 1. Churchill Livingstone; 2000:656-62.

McMillan JA, Weiner LB, Higgins AM, Lamparella VJ: Pharyngitis associated with herpes simplex virus in college students. Pediatr Infect Dis. 1993;12:280-4.

Paradise JL. Etiology and management of pharyngitis and pharyngotonsillitis in children: a current review.Ann Otol Rhinol Laryngol Suppl. 1992 Jan;155:51-7.

Patel NN, Patel DN. Acute exudative tonsillitis. Am J Med. Jan 2009;122(1):18-20.

Perkins A. An approach to diagnosing the acute sore throat. Am Fam Physician. 1997 Jan;55(1):131-8, 141-2.

Twefik TL, Al Garni M. Tonsillopharyngitis. Clinical highlights. J of Otolaryngology. 2005;34.



About The Authors

Iliyan Todorov
Medical University of Varna

Department of Infectious Diseases, Parasitology and Dermatovenereology, Faculty of Medicine, Medical University of Varna

Dimitrichka Bliznakova

Department of clinical medical sciences, Faculty of Dental Medicine, Medical University of Varna

Christiana Madjova

Department of conservative dentisty and oral pathology, Faculty of Dental Medicine, Medical University of Varna

Tsvetan Tonchev

Department of oral and maxillofacial surgery and special imaging diagnostics, Faculty of Dental Medicine, Medical University of Varna

Margarita Gospodinova

Department of Infectious Diseases, Parasitology and Dermatovenereology, Faculty of Medicine, Medical University of Varna

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