Acid-base properties of substituted 6-nitro-N-(R-phenyl)anthranilic acids

Hanna Yeromina; Olena Sviechnikova; Lina Perekhoda; Irina Sych

doi:10.14748/ssp.v1i1.1009

Acid-base properties of substituted 6-nitro-N-(R-phenyl)anthranilic acids

Hanna Yeromina, Olena Sviechnikova, Lina Perekhoda, Irina Sych

Abstract

The ionization constants of nine substituted 6-nitro-N-(R-phenyl)anthranilic acids have been determined in a mixed solvent dioxane-water at a temperature of 25ºC. The influence of the nature and positions of substituents in the non-anthranilic fragment of molecule on acid-base properties has been analyzed. The correlation equation of the relationship between pKa and GammettÊ¼s Ïƒ-constants has been calculated and low sensitivity of the reaction center to the influence of the substituents in the non-anthranilic fragment of molecule has been shown.

Keywords

substituted 6-nitro-N-(R-phenyl)anthranilic acids; ionization constants; correlation equation

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DOI: http://dx.doi.org/10.14748/ssp.v1i1.1009