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Quercetin and its effect on atherosclerosis

Alexander Boyadzhiev, Georgi Shopov, Georgi Radev


Flavonols are class of naturally occurring compounds commonly found in vegetables and fruits. As a representative of them, quercetin has benefits in different aspects. The most important of them is its role as an antioxidant. It is believed to be an effective radical scavenger that can inhibit the oxidation of lipoproteins. This flavonol possesses an antiatherogenic property as well as an antihypertensive one.
We performed a detailed review of related articles. The information that we found was objectively analyzed and systematized.
The research showed that quercetin can prevent the development of atherosclerosis due to the protection against oxidative stress, endothelial dysfunction, and inflammation. We found materials about laboratory tests including mice supplemented with quercetin. The results proved the reduction of atherosclerotic plaques by 78% and 40% less formation of them.
Considering all results, we can make a conclusion that intake of quercetin alone or along with exercises helps in the reduction of atherosclerotic plaque formation. Due to its anti-oxidative and anti-inflammatory properties, this flavonol has the opportunity to affect the pathophysiology of the atherosclerotic disease.


quercetin, flavonols, antioxidant, atherosclerosis



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About The Authors

Alexander Boyadzhiev
Medical University of Varna

Students, Faculty of Medicine

Georgi Shopov
Medical University of Varna

Students, Faculty of Medicine

Georgi Radev
Medical University of Varna

Students, Faculty of Medicine

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