The publication presents the results of complex research and analysis of medicinal plain-like of flora of Ukraine. Lycopodiophyta of Ukraine includes four families: Lycopodiaceae (8 species – Diphasiastrum alpinum (L.) Holub, D. complanatum (L.) Holub, D. isseleri (Rouy) Holub, D. tristachyum (Pursh) Holub, D. zeilleri (Rouy) Holub, Lycopodiella inundata (L.) Holub, Lycopodium annotinum L., L. clavatum L.), Huperziacaeae (1 – Huperzia selago (L.) Bernh. ex Schrank & C. Mart.), Selaginellaceae (2 – Selaginella helvetica (L.) Spring., Selaginella selaginoides (L.) C. Mart.) and Isoëtaceae (1 – Isoëtes lacustris L.). They have different contents of biologically active substances and all of these species are medicinal or semi-medicinal. The paper presents the characteristics of their distribution in Ukraine, resource importance, population structure, environmental protection status in Ukraine and Europe, main active substances, and medicinal properties.
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