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Varna Medical Forum

Application of the International Prostate Symptom Score in patients with benign prostatic hyperplasia and large gland volume

Toni Statelov

Abstract

Benign prostatic hyperplasia with large gland volume considerably disturbs patients’ individual quality of life. In recent years, a contemporary specialized International Prostate Symptom Score has been introduced among these patients in other countries. The results from the use of this score in 28 patients treated by means of transurethral thulium laser vapor resection and vaporization during the period between 2015 and 2018 at Maichin Dom Multiprofile Hospital for Active Treatment – Varna, are presented. The patients were at a mean age of 72.61 ± 7.765 years (range, 56 to 83 years) and with a mean prostatic volume of 156.71 ± 43.014 mL (range, 90 to 260 mL). The average total International Prostate Symptom Score in all patients prior to the operation amounted to 28.50 (range, 22 to 35), corresponding to a severe degree of disturbed quality of life. After three months, a considerable reduction of this score down to 2.14 (range, 0 to 5) occurred, which testified to a substantial improvement in the quality of life parameters analyzed. The main rating of the individual quality of life of patients with urinary symptoms also diminished considerably following the operative intervention (from 5.46 down to 0.61), proving their improvement in quality of life. Transurethral thulium laser vapor resection and vaporization in patients with benign prostatic hyperplasia is very effective in terms of improving quality of life.


Keywords

benign prostatic hyperplasia, large prostate, International Prostate Symptom Score, thulium laser vaporization, individual quality of life, adult patients

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References

Aybal HC, Yilmaz M, Barlas IS, Duvarci M, Guven S, Tunc L. HoLEP versus ThuFLEP in men with very large prostates (>175 ml). World J Urol. 2025;43(1):109. doi:10.1007/s00345-025-05478-8

Behzad Abbasi B, Abbasi-Kangevari M, Beshir Ahmed M, Almidani O, Amini E, Arabloo J, et al.; GBD 2019 Benign Prostatic Hyperplasia Collaborators. The global, regional, and national burden of benign prostatic hyperplasia in 204 countries and territories from 2000 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Healthy Longev. 2022;3(11):e754–e776. doi:10.1016/S2666-7568(22)00243-4

Bhatia S, Bhatia A, Richardson AJ, Richardson K, Issa C, Kumar JG, et al. Prostatic artery embolization: mid- to long-term outcomes in 1,075 patients. J Vasc Interv Radiol. 2025;36(3):456–466. doi:10.1016/j.jvir.2024.11.019

Chen X, Zhao K, Wang H, Zhang C, Du L, Wang W, et al. Trans-rectovesical pouch urethral-sparing robotic-assisted simple prostatectomy: a case series. BJUI Compass. 2024;5(8):776–782. doi:10.1002/bco2.279

Hawks-Ladds N, Tawfik MM, Babar M, Zhu M, Loloi J, Labagnara K, et al. Long-term water vapor thermal therapy outcomes across a broad range of prostate volumes. Urol Pract. 2024;11(4):727–734. doi:10.1097/UPJ.0000000000000421

Krismanuel H, Tjhin P. Examining the effectiveness of prostatic hyperplasia education on the level of participant's knowledge and awareness. PLoS One. 2025;20(6):e0325653. doi:10.1371/journal.pone.0325653

Lewer O, Felice MD, Copelan O, Janakiraman S, Pahouja G, Wozniak A, et al. Prostate size and its effect on lower urinary tract symptoms/benign prostatic hyperplasia improvement after convective water vapor thermal therapy. J Urol. 2025;214(1):48–57. doi:10.1097/JU.0000000000003462

Lin D, Luo C, Cui K, Xu H, Yuan H, Luan Y, et al. 1470 nm diode laser enucleation versus bipolar transurethral resection of the prostate for the surgical management of benign prostatic hyperplasia: a randomized comparison. Lasers Med Sci. 2025;40(1):226. doi:10.1007/s10103-025-04478-9

Manfredi M, Fiori C, Peretti D, Piramide F, Checcucci E, Garrou D, et al. Laparoscopic simple prostatectomy: complications and functional results after five years of follow-up. Minerva Urol Nefrol. 2020;72(4):498–504. doi:10.23736/S0393-2249.20.03814-5

Matsuzaki T, Yoshida T, Murota T, Nakao K, Taguchi M, Kinoshita H, et al. Complete intraureteral stent placement relieves daytime urinary frequency compared with conventional placement in patients with an indwelling ureteral stent: post-hoc analysis of a randomized, controlled trial. Sci Rep. 2020;10(1):15892. doi:10.1038/s41598-020-72937-0

Mo Q, Wang F, Liang H, Li Y, Qin M, Cheng J. Tracking and analysis of benign prostatic hyperplasia and prostate cancer burden globally: 1990–2021 epidemiological trends. Transl Androl Urol. 2025;14(3):764–778. doi:10.21037/tau-24-47

Mooney R, Goldberg K, Wong D, Roehrborn C. Convective radio frequency thermal therapy for treatment of benign prostatic hyperplasia: single office experience with 255 patients over 4 years. Urol Pract. 2020;7(1):28–33. doi:10.1097/UPJ.0000000000000079

Pacini M, Lambertini L, Avesani G, Torres Anguiano JR, Morgantini L, Martin A, et al. Single-port transvesical simple prostatectomy for the surgical treatment of benign prostatic hyperplasia: functional and continence outcomes. Prostate Cancer Prostatic Dis. 2025;28(2):451–456. doi:10.1038/s41391-024-00784-0

Re C, Longoni M, Rosiello G, Finazzi Agrò E, Gontero P, Grossi FS, et al. Current management of patients affected by benign prostatic hyperplasia: a multi-institutional study from a contemporary large Italian cohort. Minerva Urol Nephrol. 2025;77(2):239–246. doi:10.23736/S0393-2249.24.04812-2

Ringler R, Gangwish D, Horning P, Kuperus J, Palmateer G, Zwaans BMM, et al. Does size matter? A single institution's comparison of aquablation in prostates greater than or less than 150 mL. Prostate. 2025;85(2):140–147. doi:10.1002/pros.24573

Sahu S, Parmar K, Kumar S, Tyagi S, Mandal S, Devana SK, et al. Effect of transurethral resection of the prostate on urodynamic parameters in patients with benign prostatic enlargement with upper urinary tract dilatation. Urol Int. 2021;105(9–10):846–851. doi:10.1159/000517540

Shuai H, Xu P, Xu Q, Luo J, Zhou L, Zhou J, et al. Comparison of the efficacy and safety of robotic-assisted simple prostatectomy and laser enucleation of prostate for large benign prostatic hyperplasia. J Robot Surg. 2023;17(6):2687–2695. doi:10.1007/s11701-023-01566-4

Zhang P, Dong W, Liu T, Liu T, Huang X. Does the resected prostatic weight ratio affect the clinical outcomes in men who underwent bipolar transurethral resection of the prostate? Urol J. 2022;19(1):83–88. doi:10.22037/uj.v19i.7003




DOI: http://dx.doi.org/10.14748/vmf.v14i2.10483

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