Abstract
If science is the pursuit of communicable truth and reason; and one which aims to explain natural phenomena, then the continued disregard of murburn concept by research communities is condemnable (particularly: xenobiotic/drug metabolism and mitochondrial physiology fields). Therefore, if one could call a spade a spade, then such a cognitive dissonance and disowning of professional mandates by individuals and institutions MUST be called out. Such ‘status quo’ maintaining outlooks of leadership waylay the interest of the vast majority of our current and all of our future generations, and only serves to preserve the false prestige of a misplaced few at the helms! For, murburn concept is not just a novel explanatory umbrella of life’s chemico-physical foundations with profound impact on health-medicine sectors, imbibing it would also pose immediate and far-reaching impacts in education, research, philosophy and culture.
Keywords
murburn concept, redox/xenobiotic/drug metabolism, cellular/mitochondrial respiration, cytochrome P450, ATP synthesis, iconoclasm, paradigm shift, professional ethics
References
Kelath Murali Manoj. Murburn concept and murzymes in 2023: Celebrating 25th year of pursuit. Biomed Rev 2022;33:1-15. DOI: 10.14748/bmr.v33.9115
Kelath Mural Manoj, et al. Murburn concept in cellular function and bioenergetics, Part 1: Understanding murzymes at the molecular level. AIP Adv 2023;13(12) id.120702, 22pp. DOI: 10.1063/5.0171857 & Part 2: Understanding integrations-translations from molecular to macroscopic levels. AIP Adv 13(12) id.120701, 23pp. DOI: 10.1063/5.0171860
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